Andy Samberg

Ben Reilly (voice), Ben Reilly / Scarlet Spider (voice)

Pawbert Lynxley (voice)

Additional Voices (voice)

Andy Samberg

Ben Reilly (voice), Ben Reilly / Scarlet Spider (voice)

Rip Digman

Dale (voice)

Johnny (voice), Johnny Loughran (voice)

Co-Host

Benedict Arnold (voice)

Nyles

Self

Johnny Loughran (voice)

Jonathan Loughran (voice)

Johnny

Conner Friel

Nicolas Cage (voice)

Self

Johnny Loughran (voice)

DJ Nerd (voice), Dr. Nerd (voice)

Toga #1

Self

Jake Peralta

Van King

Male Cheerleader

Jonathan Loughran (voice)

Jesse Abrams

Casual Wanker #1

Todd Peterson

Gerry Perry

Jake Peralta

Quincy

Self

Carl

Robbie Klaven

Homeless Man

Rod Kimble

Ricky the Raptor / Antichrist (voice)

Jake Peralta

Self - Guest

Ham III (voice)

Self - Guest

Host

Self

Scott Garbaciak, Announcer, Zombie, Beatnik, Convoluted Jerry, DJ Davvincii, Cop, Self - Host, Scott, Carl, Self - Cameo (uncredited), Self - Various Characters, Self, Ras Trent, Singer, Host of Science Finders, Self / Admiral Spaceship, Shy Ronnie, Batman, Businessman, Thomas, Nerdy Guy, Dennis, Grape Jelly, Ariel, Conner4real, Admiral Spaceship, Andy Samberg

Host

(voice)