Maya Rudolph

Jean Dewberry

Dr. Vlam

Cynthia Utrom (voice)

Malvina Monroe, Malvina

Cass

Molly Novak

Connie

Co-Host

Daniela Paguro (voice)

Linda Mitchell (voice)

Nanny (voice)

Norma, Betty Hart, Dr. Chakrabarti, Jewel Thief

Naomi

Bubbles

Christine Davenport

Aunt Cass

Nest, Connie, Principal Barren, Ghost of Whitney Houston, Bath Mat, Miss Clinkscales, Ghost of Elizabeth Taylor, Pornscape Residents, Susan, The Pill, Parrot, Exterminator #2, Diane Birch, Gayle King, Paula, Bonnie, Judge

Smiler (voice)

Eunice

Deborah

Brinda

The Lounge Singer

Self - Guest

Griselda (voice)

Petunia Leeway

Aunt Cass (voice)

Self

Self

Self

Deanne McKenzie

Griselda Blanco

Leslie

Ava Alexander

Self

Self

Deanne McKenzie

Casey Janine Fitzpatrick

Self

Self

Rapunzel (voice)

Stacy

Self

U.S. Marshal Karen Haas

Self

Jamilla

Chloe (voice)

Delivery Nurse

Self - Guest

Julia (voice)

Self - Cameo (uncredited), Maya Rudolph, Self, Self - Host, Self - Various Characters