Eternal Moonshine of the Simpson Mind

Homer wakes up in the snow with no memory of what he did the night before--and begins fearing the worst when his family ends up missing, Chief Wiggum tells Homer that there was a domestic disturbance at 742 Evergreen Terrace, and Moe tells Homer that he drank a "Forget Me Shot" (a potent cocktail that erases the last 24 hours of a person's life) to get rid of something horrible he did the day before.